Annual Report of the Scientific Director

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Excerpt from Annual Report of the Scientific Director: October 1, 1991 to September 30, 1992A scientific program as large and diversified as that of the nhlbi Division of Intramural Research cannot be summarized in a few pages. Perhaps what can be done by appropriately chosen examples is to capture its flavor and to highlight a few selected accomplishments from among the many that are described in the pages that follow.For a number of years, the dir has been of relatively constant size with about 70 tenured, doctoral - level scientists, a total staff of about 550 and about 150 doctoral-level guest scientists. The dir occupies about square feet of space in 6 buildings and clinical investigators have the use of about 80 beds in 4 different patient care units. The total budget is about which includes about for laboratory operating expenses and equipment purchases and about to support clinical research.This year a number of major renovations of laboratory space were completed or are in progress, including about 5 laboratories in Building 3 to house an expanded nmr facility for the study of the 3-dimensional structure of macromolecules, about 30 laboratories and administrative offices in Building 10, most of which had not been renovated since their initial occupancy in 1953-1954, and the conversion of a patient care unit into the first research bone marrow transplantation unit at the nih, which should open early in 1993. In addition, construction is now underway for about square feet of laboratory and animal holding space in a rented building off campus. This will allow significant expansion of animal research, especially with non-human primates, as part of the Institute's expanding efforts toward developing genetic therapy for a number of pulmonary, cardiovascular and blood diseases.Although the dir remains essentially unchanged organizationally, the orientation of the research continues to move at an ever increasing pace towards macromolecular structure, molecular biology and genetics and molecular medicine including, as mentioned, gene therapy although more traditional clinical research is still, and will continue to be, well supported. In this context, the resignation of Dr. N. French Anderson who left the Institute to join his wife who accepted a major position in Los Angeles should be noted. Fortunately, Dr. Anderson has left a cadre of well - trained investigators who will continue the research he initiated and other Branch Chiefs have followed his lead in establishing their own independent programs.About the PublisherForgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.comThis book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully, any imperfections that remain are intentionally left to preserve the state of such historical works.