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- Antitargets
Antitargets
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Addressing a common challenge that is faced by every drug developer, this practice-oriented handbook surveys current knowledge on the occurrence and prevention of adverse drug reactions related to off-target activity of small molecule drugs.
It is unique in collating the current approaches into a single source, and includes several highly instructive case studies that may be used as guidelines on how to improve drug development projects.
Clearly divided into four parts, the first covers general considerations of studying and predicting side effects in drug molecules, while the second part looks at well-known anti-targets that mediate severe side effects. Part three covers the large field of ADME-related effects, focusing on the prevention of cytochrome induction and on drug transporters. The final part presents selected case studies of successful drug development in terms of suppressing unwanted side effects.
The result is key knowledge for medicinal and pharmaceutical chemists, toxicologists, molecular biologists, and pharmaceutists as well as drug developers working in the pharmaceutical industry.
Lieferbar in ca. 10-20 Arbeitstagen