Clinical Neurobiology of Atypical Psychoses

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After 1980, operational diagnostic methods, such as the DSM-III, became reliable international standards. During this period, the concept of atypical psychoses was sidelined and considered to be outdated because of their emphasis on symptoms with low objective evaluation. Operational diagnostic criteria are clear-cut and easily understandable, and are valuable for medical students, nursing staff, and basic researchers. However, in recent years, internal critique was submitted from a notable American psychiatrist involved in drafting of the DSM diagnostic criteria, who put forth the limitations of the operational diagnostic methods. Facing the shortcomings of these operational diagnostic methods, many psychiatrists are aware of the superficiality of this diagnostic system. The importance increases in disease classification based on "nosology" and in detailed clinical investigations concerning psychiatric symptoms and clinical course. Despite much criticism, atypical psychoses still surv

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