Effects on Diabetes in Experimental Rats

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This book is a detailed guide that explores the pharmacological properties of a herbal mixture called Goa-111 in high-fat diet fed low-dose streptozotocin-induced experimental type II diabetes in rats. The book provides a comprehensive overview of the effects of this mixture on the regulation of blood glucose, lipid profile, and antioxidant status in diabetic rats. The book describes the preparation and standardization of the herbal mixture containing Gymnema sylvestrae, Ocimum sanctum, and Azadirachta indica extracts in the ratio of 1:1:1. It discusses the phytochemical composition and therapeutic potential of each component of the mixture and their synergistic effects on diabetes. Furthermore, the book presents the experimental results that show the significant anti-diabetic effects of the herbal mixture, such as improved glucose tolerance, increased insulin sensitivity, reduced fasting blood glucose, and improved lipid profile. Additionally, the mixture showed potent antioxidant activity by reducing oxidative stress and increasing antioxidant enzyme activity in diabetic rats. Overall, book is a valuable resource for researchers, healthcare professionals, and students interested in the field of herbal medicine and diabetes. It provides a detailed understanding of the pharmacological properties of a herbal mixture in the regulation of diabetes and its associated complications. The book highlights the potential of Goa-111 as a safe and effective natural remedy for the management of type II diabetes.