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  • IARC Handbooks of Cancer Prevention

IARC Handbooks of Cancer Prevention

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Over the past twenty years, there has been an intense interest in stud ying vitamin A as an active chemopreventive agent. Observational epide miological studies have not shown consistent cancer-preventive effects . Vitamin A, often in combination with other compounds, has been studi ed in several randomized trials. Overall, there is little evidence tha t supplementation for a few years would reduce the risk of any type of cancer. This book summarizes and evaluates the existing evidence on t he cancer-preventive activity of vitamin A. On 13-19 May 1998, a worki ng group of international experts met in Lyon to evaluate the existing evidence on the cancer-preventive activity of retinol and retinyl est ers.
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