Identification of Nonlinear Physiological Systems

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A comprehensive reference for nonlinear identification of biomedical systems System identification encompasses a set of tools that construct mathematical models of dynamic systems from measurements of their inputs and outputs. Since many of the systems that are of interest to biomedical engineers and physiologists are nonlinear, mathematical models of nonlinear systems, and methods to construct them from experimental measurements, are required. Identification of Nonlinear Physiological Systems presents the methods used to identify models of nonlinear systems from measurements in order to enable readers to make informed decisions regarding which techniques are likely to be most applicable to a given system or experiment. Providing both the theoretical background of the methods and practical advice on how to implement, apply, and interpret the results of these methods, the book: * Reviews linear system models that are the bases for nonlinear models * Develops nonlinear system models with an emphasis on the relationships between them * Includes running MATLAB(r) examples to illustrate the results obtained by different methods when applied to the same data * Details the relationships between various approaches and discusses their relative strengths and weaknesses * Presents the results from several key studies employing system identification methods Recent advances in such fields as high throughput genomics and proteomics and growing interest in the new paradigm of systems biology are making an understanding of nonlinear systems ever more urgent. Identification of Nonlinear Physiological Systems is a welcome reference for anyone involved in the study of the nonlinear dynamic behavior of biomedical systems.