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- Multifaceted Role of IL-1 in Cancer and Inflammation
Multifaceted Role of IL-1 in Cancer and Inflammation
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Interleukin-1 Mediated Immune Suppression and Resistance to Immunotherapy in Cancer summarizes the existing literature and discusses future perspectives about the role of IL-1 in immune suppression, cancer progression, angiogenesis, and resistance to immunotherapies. It also presents mechanisms to overcome IL-1 mediated immune suppression in tumor microenvironment. The book covers topics about the source of IL-1 in the tumor microenvironment, IL-1 mediated downstream pathway, mechanism of IL-1 mediated immune suppression in cancer, and its effect on immunotherapy of cancer. Those topics help readers to understand the effect of IL-1 on cancer immunopathology and immunotherapy, and provide them with broader concepts to develop therapies for IL-1 enrichment tumors. It is a valuable source for cancer researchers, clinicians and other members of biomedical field who wants to learn more about mechanisms to improve outcome of cancer immunotherapies.
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