Mechanisms of Morphogenesis

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Morphogenesis is the set of processes that generate shape and form in the embryo, an important and increasingly researched area within developmental biology. Providing an exciting and up-to-date account of the latest research into the factors that create biological form, Mechanisms of Morphogenesis, Third Edition offers a bottom-up discussion of mechanisms of cell and tissue morphogenesis in a diverse array of organisms, including prokaryotes, animals, plants, and fungi. Across foundational, applied, and methods-based chapters, this book examines how molecular nano-machines cooperate, generate cell shape, direct cell migration, and to produce the shape, form, and rates of growth of various tissues in the body. Each topic is illustrated with experimental data from real systems, with particular reference to gaps in current knowledge and likely future developments, along with strategies to apply basic morphogenesis science across ever evolving applications. Newly added chapters feature case-study-driven discussions of morphogenesis in natural embryos and organoids, and illustrate how pathological morphogenesis can generate variants of body form. This edition has also been updated with analysis of large-scale and scale-invariant mechanisms, for example, morphogenesis by differential growth in mechanically connected tissues.