National Institute of Allergy and Infectious Diseases, Annual Report of Intramural Activities

Angebote / Angebote:

Excerpt from National Institute of Allergy and Infectious Diseases, Annual Report of Intramural Activities: October 1, 1992 September 30, 1993Simian immunodeficiency virus (siv) infection of macaque monkeys is a relevant animal model to test potential vaccine strategies for aids. LID researchers have used this animal model to study various vaccines. Studies were initiated with a killed whole virus vaccine. This vaccine protected immunized animals from infection with cell-free virus but not from siv-infected cells. Although immunized animals that were challenged with infected cells became infected, their survival was greatly prolonged as compared to unvaccinated monkeys. Another vaccine that is currently being tested involves the use of vaccinia virus vectors to express viral proteins of siv. These studies use a vaccinia virus that has been modified to express large amounts of the siv envelope protein and also altered so as not to induce a lesion at the site of vaccination.About the PublisherForgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.comThis book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully, any imperfections that remain are intentionally left to preserve the state of such historical works.