Next Generation Sequencing in Cancer Research

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Next Generation Sequencing (NGS) technology has placed importantmilestones in the life science and changed the directionin biomedical science inclucing cancer. Scientists around theworld are attempting to find the root cause of cancer and theyare looking for more direct and effective means to cure cancer.This journey to conquer cancer is more optimistic now withthe unfolding of the cancer genome. This book focuses on theapplication of various NGS in the frontier cancer genome research.The 18 chapters in this volume have been written byscientists with many outstanding contributions in their areaand the join effort has created comprehensive insightful viewon (1) Overview of next generation sequencing technology incancer genome research (2) Genome regulation and targetedsequencing in cancer (3) RNA transcriptome (coding andnon-coding) in cancer genome (4)The challenges of computationalbiology for cancer genome study.This book is a state-of-the-art reference to all scientific researchersand onologists who are interested in the understandingof the cancer initiatome at whole genome scale and to thoseare keen to translate the ‘base pairs to bedside’ for better managementof cancer patients in the era of personalized medicine.