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- Pathogenic Treponema
Pathogenic Treponema
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In the past, Treponema research was severely handicapped because the organisms were notoriously difficult to work with and were unculturable in the laboratory. Powerful molecular and genetic tools developed in recent years have been successfully used to dramatically expand our understanding of treponemal diversity, genomics, and cellular and molecular biology. Major breakthroughs include sequencing of Treponema genomes and the development of modern molecular methods. In recent years there has been an explosion of new information that is summarized in the current volume. Expert international authors critically review every aspect of the molecular and cellular biology of these fascinating organisms. The focus of this book is on recent advances and new developments in Treponema research, in particular those resulting from modern molecular and genetic methodologies. Topics covered include the phylogenic diversity, comparative genomics, metabolism and cultivation, motility, antigenic varia
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