Pyrazole-Based Drug Discovery

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Pyrazole-Based Drug Discovery outlines complexities of the pyrazole scaffold used in drug discovery, including derivative chemistry, structural properties, methods of synthesis, and practical implementations. Designed as a guide for both experts and students working in this and related areas, this volume will facilitate the continued design and development of novel pharmaceuticals based on pyrazole and its derivatives. Pyrazole is a novel heterocycle with anti-fungal, antimicrobial, anti-tubercular, and antipsychotic pharmacological activities, proving to be a promising agent for medicinal chemists to synthesize various new chemical entities with desired biological activities. Heterocyclic compounds are of central importance to medicinal chemistry, as demonstrated by the high percentage of marketable drugs that feature heterocyclic fragments in their structures. As starting points for drug discovery, they offer a broad range of attractive properties, and a detailed understanding of the particular characteristics of each is of great benefit to researchers. This book is ideal for researchers working in organic and medicinal chemistry both in academia and industry.