Seventh Scientific Report on the Investigations of the Imperial Cancer Research Fund

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Excerpt from Seventh Scientific Report on the Investigations of the Imperial Cancer Research Fund: Under the Direction of the Royal College of Physicians of London and the Royal College of Surgeons of England The significance of this phenomenon lies, apart from its theoretical importance, in the fact that it reveals a phase of diminished vitality in the life of the cancer cell which may serve as a guide in an attempt to find a rational therapeutic of cancer. Since cancer cells are subject to senescence, it is not unreasonable to expect that a knowledge of the factors on which this spontaneous process of sensecence depends may enable us to find conditions which might favour or maintain this process or even induce it. At present nothing is known about the factors which induce this process spontaneously. As to the nature of the process we have shown in a previous paper that the parallelism between rate of growth and degree of imbibition holds good for these ¿uctuations in the rate of growth in one and the same tumour strain. The phenomenon of the inhibition of growth recorded in this paper might be described as an experimental senescence of cancer cells, which it simulates also in showing the Spontaneous rejuvenescence. It is obvious that the conditions by which senescence has been induced in vitro are crude compared with those which determine it in vivo. At present all that can be claimed for this experiment is that it affords an insight into the nature of the processes which lead to a temporary diminution of the vitality of cancerous cells. About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully, any imperfections that remain are intentionally left to preserve the state of such historical works.