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- The Chicago Medical Journal and Examiner, Vol. 43
The Chicago Medical Journal and Examiner, Vol. 43
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Excerpt from The Chicago Medical Journal and Examiner, Vol. 43: July to December, 1881
It was not, however, until the recent experiments for the pro tection of animals and fowls against anthrax and chicken cholera, that all difficulty was removed from consideration of the problem. Pasteur, Toussaint, and others, in France and Germany, found that by attenuating the virus of chicken cholera, and by heating the blood or other liquids of anthrax, a dilute form of the specific poison was produced, which, when injected into a healthy animal, excited a modified, and generally non-fatal form of the disease, by which the animal was completely protected against the fully virulent form of the contagion. Here, then, we find an explana tion of the manner in which the virus of bovine variola differs from the virus of human variola - it is variolous virus attenuated, diluted or modified by the action of the bovine tissues, so that, while it does not excite the general eruption of variola in the human subject, it does yet, when used for vaccination, so sufh ciently modify the human tissues that they become tolerant of the fully virulent poison of unmodified human small-pox.
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